HitPredict

Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	22692198, 35799276, 16964240, 16861890
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0034644 - cellular response to UV
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 759
+	Mm
		572247 PCNA_MOUSE (1-261): 1.25e-125: 358: 96.94		CUL4A_MOUSE (1-759): 0: 977: 95.13
+	Hs
		517248 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		517246 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		517244 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		517245 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Dm
		572202 PCNA_DROME (1-259): 1.18e-122: 351: 71.04		Q9V9R2_DROME (51-759): 0: 657: 24.44
+	Hs
		517394 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Dm
		1196761 Q868I9_DROME (1-36): 3.11e-09: 53.1: 63.89		Q9V9R2_DROME (51-759): 0: 657: 24.44