Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: PAF15 (Q15004)
PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor)
Gene: PCLAF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 21700221, 11313979, 36734974, 16288740, 21628590, 26186194, 26496610, 28514442, 32296183, 33961781, 24958773, unassigned1304
Identification Methods pull down, affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAF~PCNA_C, PAF~PCNA_N
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0019985 - translesion synthesis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 261
Hs

1 111
+ Xl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024