Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 27634302, 36517590
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 261
Hs

1 746
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024