Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 28924044, 30563767, 32701997, 23345618, 24958773, 22904075, 26170230, 28831681, 27377895, 31160570, 31873223, 31887036, 30700555, 18363965, 33508099, 35459258, 35355521, 20675655, 21858012, 20600238 and 7 others

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Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
GO:0005813 - centrosome
and 2 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 261
Hs

1 495
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024