HitPredict

Interactor 1: A1Z6R7 (A1Z6R7)
FI21445p1
Gene: DmelCG30158

Interactor 2: Q7JWS8 (Q7JWS8)
AT17867p (Mig-2-like GTPase Mtl) (Mig-2-like, isoform A) (Mig-2-like, isoform B) (Mig-2-like, isoform C) (Small GTPase)
Gene: Mtl

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 280 Dm			1 195
+	Hs
		918847 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RAC1_HUMAN (4-195): 1.79e-84: 249: 70.83
+	Hs
		925294 RAB35_HUMAN (7-183): 8.95e-80: 241: 28.09		RAC1_HUMAN (4-195): 1.79e-84: 249: 70.83
+	Hs
		925600 RAB1B_HUMAN (4-205): 2.14e-79: 240: 28.57		RAC1_HUMAN (4-195): 1.79e-84: 249: 70.83
+	Hs
		545307 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RAC2_HUMAN (4-195): 3.98e-81: 240: 67.19
+	Hs
		545392 RAB35_HUMAN (7-183): 8.95e-80: 241: 28.09		RAC2_HUMAN (4-195): 3.98e-81: 240: 67.19
+	Hs
		564470 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RHOQ_HUMAN (7-190): 8.34e-78: 233: 59.78
+	Hs
		918849 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RHOG_HUMAN (4-195): 3.92e-78: 233: 64.58
+	Hs
		893872 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		CDC42_HUMAN (4-195): 7.8e-78: 232: 62.50
+	Hs
		900355 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RHOA_HUMAN (1-195): 7.31e-78: 232: 55.39
+	Hs
		892305 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RAC3_HUMAN (4-194): 1.83e-77: 231: 67.54
+	Sc
		533751 RSR1_YEAST (4-235): 2.82e-80: 245: 25.87		CDC42_YEAST (4-195): 2.61e-76: 228: 60.42
+	Hs
		894031 RAB35_HUMAN (7-183): 8.95e-80: 241: 28.09		CDC42_HUMAN (4-195): 7.8e-78: 232: 62.50
+	Hs
		900494 RAB35_HUMAN (7-183): 8.95e-80: 241: 28.09		RHOA_HUMAN (1-195): 7.31e-78: 232: 55.39
+	Zm
		73944 B4FAE1_MAIZE (4-207): 5.79e-81: 244: 27.32		B4FAE1_MAIZE (3-193): 5.51e-76: 228: 22.92
+	Hs
		892386 RAB35_HUMAN (7-183): 8.95e-80: 241: 28.09		RAC3_HUMAN (4-194): 1.83e-77: 231: 67.54
+	Hs
		894409 RAB1B_HUMAN (4-205): 2.14e-79: 240: 28.57		CDC42_HUMAN (4-195): 7.8e-78: 232: 62.50
+	Hs
		900882 RAB1B_HUMAN (4-205): 2.14e-79: 240: 28.57		RHOA_HUMAN (1-195): 7.31e-78: 232: 55.39
+	Hs
		436244 RAB1A_HUMAN (1-206): 1.31e-80: 243: 28.30		RHOC_HUMAN (1-195): 1.2e-75: 226: 55.39
+	Hs
		436498 RAB1B_HUMAN (4-205): 2.14e-79: 240: 28.57		RHOC_HUMAN (1-195): 1.2e-75: 226: 55.39
+	Hs
		436232 RAB2A_HUMAN (1-203): 4.33e-76: 232: 24.02		RHOC_HUMAN (1-195): 1.2e-75: 226: 55.39