Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: POLK (Q9UBT6)
DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)
Gene: POLK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 16611994, 20227374, 26903512, 34667155, 22157819
Identification Methods affinity chromatography technology, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS_C~PCNA_N
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016604 - nuclear body
GO:0034644 - cellular response to UV
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 261
Hs

1 870
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Sp
+ At
+ At
+ Ce
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024