Interactor 1: A4 (P12023)
Amyloid-beta precursor protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta (A4) precursor protein) (Amyloid-beta A4 protein) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99) (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (APP-C59) (Amyloid intracellular domain 59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (APP-C57) (Amyloid intracellular domain 57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AID(50)) (Gamma-CTF(50)); C31]
Gene: App
Interactor 2: APLP1 (Q03157)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.64 | 1.00 | 0.806 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | APP_Cu_bd~APP_Cu_bd, APP_Cu_bd~APP_N, APP_E2~APP_E2, APP_N~APP_N |
Common GO terms | GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0006417 - regulation of translation GO:0007155 - cell adhesion GO:0006897 - endocytosis and 10 others more... |
Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024