HitPredict

Interactor 1: ADT3 (P12236)
ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene: SLC25A6

Interactor 2: VDAC1 (P21796)
Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)
Gene: VDAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29128334, 21370995
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0006915 - apoptotic process GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 283
+	Mm
		851090 ADT2_MOUSE (1-297): 3.08e-111: 325: 91.25		VDAC1_MOUSE (1-283): 9.77e-112: 326: 98.59
+	Hs
		397268 ADT2_HUMAN (1-297): 8.7e-111: 324: 92.26		VDAC1_HUMAN (1-283): 1.37e-110: 322: 100.00
+	Hs
		518085 ADT1_HUMAN (1-298): 6.2e-111: 324: 88.26		VDAC1_HUMAN (1-283): 1.37e-110: 322: 100.00
+	Hs
		601399 S2513_HUMAN (3-271): 4.13e-43: 158: 18.96		VDAC1_HUMAN (1-283): 1.37e-110: 322: 100.00
+	Sc
		389844 ADT2_YEAST (8-206): 3.48e-38: 138: 24.12		VDAC1_YEAST (4-283): 7.73e-78: 239: 24.74
+	Sc
		389843 ADT3_YEAST (107-298): 7.48e-33: 124: 18.81		VDAC1_YEAST (4-283): 7.73e-78: 239: 24.74
+	Hs
		274465 S2512_HUMAN (12-119): 3.18e-19: 89.5: 22.02		TOM40_HUMAN (4-279): 5.43e-60: 196: 12.46
+	Hs
		330686 SCMC1_HUMAN (204-298): 4.9e-16: 79.8: 15.63		TOM40_HUMAN (4-279): 5.43e-60: 196: 12.46