HitPredict

Interactor 1: ADT3 (P12236)
ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene: SLC25A6

Interactor 2: KLK6 (Q92876)
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)
Gene: KLK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 244
+	Hs
		225952 ADT1_HUMAN (1-298): 6.2e-111: 324: 88.26		KLK8_HUMAN (3-244): 4.46e-107: 311: 45.42
+	Hs
		420735 ADT1_HUMAN (1-298): 6.2e-111: 324: 88.26		KLK1_HUMAN (2-242): 3.7e-103: 301: 37.11
+	Hs
		518291 ADT3_HUMAN (1-298): 7.29e-113: 329: 100.00		KLK7_HUMAN (13-242): 8.34e-100: 292: 40.52
+	Hs
		518209 ADT1_HUMAN (1-298): 6.2e-111: 324: 88.26		TMPS4_HUMAN (5-244): 3.8e-97: 292: 32.68
+	Hs
		518527 ADT3_HUMAN (1-298): 7.29e-113: 329: 100.00		KLK9_HUMAN (19-242): 1.45e-97: 286: 43.48
+	Hs
		518369 ADT3_HUMAN (1-298): 7.29e-113: 329: 100.00		PRSS8_HUMAN (12-241): 1.32e-94: 282: 34.13
+	Mm
		371634 ADT1_MOUSE (1-298): 5.55e-112: 327: 88.93		CFAD_MOUSE (5-240): 1.65e-92: 274: 35.37
+	Mm
		371643 ADT2_MOUSE (1-297): 3.08e-111: 325: 91.25		CFAD_MOUSE (5-240): 1.65e-92: 274: 35.37
+	Hs
		198386 ADT3_HUMAN (1-298): 7.29e-113: 329: 100.00		KLK10_HUMAN (10-243): 7.27e-56: 181: 38.98
+	Hs
		1345088 S2513_HUMAN (3-271): 4.13e-43: 158: 18.96		TMPS4_HUMAN (5-244): 3.8e-97: 292: 32.68
+	Hs
		1154119 SCMC2_HUMAN (3-199): 3.97e-45: 160: 23.35		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		309915 UCP5_HUMAN (4-201): 2.99e-44: 154: 18.69		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		1085203 KMCP1_HUMAN (4-201): 3.01e-43: 151: 19.10		PRSS8_HUMAN (12-241): 1.32e-94: 282: 34.13
+	Mm
		372079 S2512_MOUSE (12-119): 1.84e-19: 90.2: 22.94		CFAD_MOUSE (5-240): 1.65e-92: 274: 35.37
+	Mm
		372108 SCMC1_MOUSE (204-298): 6.16e-16: 79.5: 15.63		CFAD_MOUSE (5-240): 1.65e-92: 274: 35.37