HitPredict

Interactor 1: IMDH2 (P12268)
Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) (Inosine-5'-monophosphate dehydrogenase type II) (IMP dehydrogenase II) (IMPDH-II)
Gene: IMPDH2

Interactor 2: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29117863
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 630
+	Hs
		518758 IMDH2_HUMAN (1-514): 0: 785: 100.00		TRIM9_HUMAN (4-591): 2.11e-79: 267: 14.85
+	Hs
		518692 IMDH2_HUMAN (1-514): 0: 785: 100.00		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		596064 IMDH1_HUMAN (1-514): 0: 766: 84.05		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		596100 IMDH1_HUMAN (1-514): 0: 766: 84.05		TRIM6_HUMAN (3-332): 6.76e-31: 128: 13.39
+	Hs
		1172086 GMPR2_HUMAN (227-494): 2.09e-108: 328: 28.36		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		739374 GMPR1_HUMAN (233-494): 2.14e-106: 323: 28.63		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73