HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29568061, unassigned1655
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2363 Hs			1 215
+	Hs
		518848 TPR_HUMAN (1-2351): 7.93e-175: 597: 100.00		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		592257 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		918867 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18
+	Hs
		844524 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		914077 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		914049 GOGA4_HUMAN (1511-2345): 2.86e-21: 104: 9.13		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Sc
		350851 USO1_YEAST (681-1585): 2.5e-12: 75.1: 19.02		YPT1_YEAST (14-213): 5.55e-88: 259: 39.02
+	Hs
		895362 CNTRL_HUMAN (2-538): 3.64e-12: 74.7: 12.68		RAB5B_HUMAN (1-215): 3.87e-85: 252: 81.86
+	Hs
		148389 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		1079932 CNTRL_HUMAN (2-538): 3.64e-12: 74.7: 12.68		RB11B_HUMAN (11-215): 1.27e-82: 246: 40.74
+	Hs
		148636 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18
+	Hs
		149274 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		RAB1B_HUMAN (13-213): 3.05e-87: 257: 41.79