HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070840 - dynein complex binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2363 Hs			1 140
+	Hs
		742130 CENPF_HUMAN (270-2309): 1.3e-43: 178: 10.34		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		724690 MYH9_HUMAN (1404-2309): 4.5e-28: 127: 9.29		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		725098 MYH10_HUMAN (2-563): 2.37e-21: 104: 15.02		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		742298 NUMA1_HUMAN (1475-2060): 2.53e-11: 72: 10.08		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		551627 DESP_HUMAN (688-1584): 5.95e-11: 70.5: 18.36		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00