Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 26496610, 12802065, 31375530, 37071682
Identification Methods affinity chromatography technology, pull down, two hybrid, fluorescent resonance energy transfer, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0006405 - RNA export from nucleus
GO:0006606 - protein import into nucleus
and 7 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2363
Hs

1 1475
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024