HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.665

The method score is based on:

Property Details
Experiments 31588029, 24938596, 24581499
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
GO:0007094 - mitotic spindle assembly checkpoint signaling
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 2363
Hs

1 718
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024