Interactor 1: LYAG (P10253)
Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase]
Gene: GAA
Interactor 2: GANAB (Q14697)
Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha)
Gene: GANAB
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Gal_mutarotas_2~Gal_mutarotas_2, Gal_mutarotas_2~Glyco_hydro_31_2nd, Gal_mutarotas_2~Glyco_hydro_31_3rd, Glyco_hydro_31_2nd~Glyco_hydro_31_2nd, Glyco_hydro_31_2nd~Glyco_hydro_31_3rd, Glyco_hydro_31_3rd~Glyco_hydro_31_3rd, Gal_mutarotas_2~Trefoil, Glyco_hydro_31_2nd~Trefoil |
| Common GO terms | GO:0016020 - membrane GO:0030246 - carbohydrate binding GO:0043231 - intracellular membrane-bounded organelle GO:0070062 - extracellular exosome GO:0090599 - alpha-glucosidase activity |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
