HitPredict

Interactor 1: TCPA (P12613)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing TCP1 subunit 1)
Gene: CCT1

Interactor 2: AKT1 (Q8INB9)
RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Protein kinase B) (PKB)
Gene: Akt

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27626673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Dm			1 611
+	Hs
		681738 TCPG_HUMAN (3-556): 0: 580: 30.14		AKT1_HUMAN (102-590): 0: 530: 59.96
+	Hs
		573141 TCPA_HUMAN (4-546): 0: 579: 73.85		AKT1_HUMAN (102-590): 0: 530: 59.96
+	Hs
		681999 TCPH_HUMAN (1-544): 0: 572: 33.64		AKT1_HUMAN (102-590): 0: 530: 59.96
+	Hs
		681735 TCPE_HUMAN (2-541): 0: 537: 30.83		AKT1_HUMAN (102-590): 0: 530: 59.96
+	Hs
		826928 TCPG_HUMAN (3-556): 0: 580: 30.14		KS6B2_HUMAN (222-609): 9.99e-155: 455: 38.04
+	Hs
		573515 TCPA_HUMAN (4-546): 0: 579: 73.85		KS6B2_HUMAN (222-609): 9.99e-155: 455: 38.04
+	Hs
		1306721 TCPH_HUMAN (1-544): 0: 572: 33.64		KS6B2_HUMAN (222-609): 9.99e-155: 455: 38.04
+	Hs
		826897 TCPG_HUMAN (3-556): 0: 580: 30.14		SGK2_HUMAN (265-597): 1.52e-145: 427: 49.55
+	Hs
		573486 TCPA_HUMAN (4-546): 0: 579: 73.85		SGK2_HUMAN (265-597): 1.52e-145: 427: 49.55
+	Dm
		520039 TCPA_DROME (1-557): 0: 570: 100.00		Q94533_DROME (225-590): 2.18e-145: 431: 40.00
+	Hs
		1306691 TCPH_HUMAN (1-544): 0: 572: 33.64		SGK2_HUMAN (265-597): 1.52e-145: 427: 49.55
+	Hs
		821449 TCPE_HUMAN (2-541): 0: 537: 30.83		KS6B2_HUMAN (222-609): 9.99e-155: 455: 38.04
+	Hs
		568585 TCPE_HUMAN (2-541): 0: 537: 30.83		KAPCA_HUMAN (243-560): 1.27e-148: 434: 40.57
+	Hs
		821419 TCPE_HUMAN (2-541): 0: 537: 30.83		SGK2_HUMAN (265-597): 1.52e-145: 427: 49.55
+	Dm
		1213398 Q9VHL2_DROME (12-535): 6.79e-84: 273: 35.03		AKT1_DROME (1-611): 0: 645: 100.00
+	Dm
		1213438 Q9W392_DROME (21-541): 1.48e-82: 269: 34.03		AKT1_DROME (1-611): 0: 645: 100.00
+	Hs
		821353 TCPE_HUMAN (2-541): 0: 537: 30.83		SGK3_HUMAN (222-562): 1.16e-107: 335: 49.86
+	Hs
		681747 TCPD_HUMAN (14-534): 7.3e-79: 259: 31.19		AKT1_HUMAN (102-590): 0: 530: 59.96
+	Hs
		568593 TCPD_HUMAN (14-534): 7.3e-79: 259: 31.19		KAPCA_HUMAN (243-560): 1.27e-148: 434: 40.57
+	Hs
		843210 TCPD_HUMAN (14-534): 7.3e-79: 259: 31.19		KS6A1_HUMAN (69-569): 6.12e-120: 374: 18.79