Interactor 1: BMP4 (P12644)
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
Gene: BMP4

Interactor 2: CALR (P27797)
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Gene: CALR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0008284 - positive regulation of cell population proliferation
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 408
Hs

1 417
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024