Interactor 1: HMDH2 (P12684)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (HMG-CoA reductase 2) (EC 1.1.1.34)
Gene: HMG2

Interactor 2: HMDH2 (P12684)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (HMG-CoA reductase 2) (EC 1.1.1.34)
Gene: HMG2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.785

The method score is based on:

Property Details
Experiments 18467557, unassigned1933
Identification Methods protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG-CoA_red~HMG-CoA_red
Common GO terms GO:0000502 - proteasome complex
GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0005635 - nuclear envelope
GO:0005778 - peroxisomal membrane
GO:0005783 - endoplasmic reticulum
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1045
Sc

1 1045
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024