HitPredict

Interactor 1: REV1 (P12689)
DNA repair protein REV1 (EC 2.7.7.-) (Reversionless protein 1)
Gene: REV1

Interactor 2: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.957

Property	Details
Experiments	26903512, 27325737, 22829782, 27537501, 17517887, 21799021, 23747975
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	IMS_C~PCNA_N
Common GO terms	GO:0005634 - nucleus GO:0005657 - replication fork GO:0070987 - error-free translesion synthesis
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 985 Sc			1 258
+	Hs
		517546 POLH_HUMAN (350-871): 2.37e-124: 396: 15.25		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Hs
		1151405 POLH_HUMAN (350-871): 2.37e-124: 396: 15.25		Q6FI35_HUMAN (1-258): 2.18e-108: 315: 35.52
+	At
		1210842 POLH_ARATH (352-870): 2.21e-117: 376: 15.91		PCNA1_ARATH (1-258): 1e-106: 311: 40.15
+	At
		1210843 POLH_ARATH (352-870): 2.21e-117: 376: 15.91		PCNA2_ARATH (1-258): 4.46e-105: 306: 39.77
+	Mm
		572264 POLK_MOUSE (347-838): 4.41e-109: 359: 15.37		PCNA_MOUSE (1-258): 5.1e-111: 322: 35.52
+	Hs
		517539 POLI_HUMAN (351-829): 1.29e-109: 358: 16.20		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Hs
		1151404 POLI_HUMAN (351-829): 1.29e-109: 358: 16.20		Q6FI35_HUMAN (1-258): 2.18e-108: 315: 35.52
+	Mm
		572263 POLH_MOUSE (350-864): 1.47e-106: 348: 14.71		PCNA_MOUSE (1-258): 5.1e-111: 322: 35.52
+	Hs
		517517 POLK_HUMAN (347-838): 7.59e-103: 343: 14.46		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Ce
		107932 G5EFY1_CAEEL (356-864): 1.47e-106: 345: 15.05		PCNA_CAEEL (1-258): 1.89e-96: 285: 40.39
+	Sp
		194856 ESO1_SCHPO (356-808): 1.96e-83: 290: 15.73		PCNA_SCHPO (1-258): 9.83e-103: 300: 44.57
+	Mm
		572259 REV1_MOUSE (131-327): 2.13e-56: 214: 31.86		PCNA_MOUSE (1-258): 5.1e-111: 322: 35.52
+	Hs
		517521 REV1_HUMAN (132-304): 1.01e-54: 209: 32.22		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Sc
		550573 POLH_YEAST (357-473): 6.95e-23: 106: 21.62		PCNA_YEAST (1-258): 5.31e-95: 281: 100.00