HitPredict

Interactor 1: ECP (P12724)
Eosinophil cationic protein (ECP) (EC 3.1.27.-) (Ribonuclease 3) (RNase 3)
Gene: RNASE3

Interactor 2: RINI (P13489)
Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI)
Gene: RNH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_6~RnaseA, LRR_RI_capping~RnaseA
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 461
+	Hs
		486368 RNAS2_HUMAN (1-160): 4.05e-68: 205: 68.94		RINI_HUMAN (1-461): 2.73e-78: 252: 100.00
+	Hs
		528027 RNAS7_HUMAN (22-160): 1.75e-53: 168: 37.41		RINI_HUMAN (1-461): 2.73e-78: 252: 100.00
+	Hs
		434682 RNAS1_HUMAN (33-160): 1.36e-44: 145: 29.85		RINI_HUMAN (1-461): 2.73e-78: 252: 100.00
+	Hs
		527957 RNAS4_HUMAN (35-158): 4.84e-40: 133: 26.36		RINI_HUMAN (1-461): 2.73e-78: 252: 100.00
+	Hs
		371352 ANGI_HUMAN (33-160): 3.65e-36: 123: 27.07		RINI_HUMAN (1-461): 2.73e-78: 252: 100.00