HitPredict

Interactor 1: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50

Interactor 2: KIN3 (P22209)
Serine/threonine-protein kinase KIN3 (EC 2.7.11.1)
Gene: KIN3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22875988
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1312 Sc			1 435
+	Hs
		1057432 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		ST38L_HUMAN (2-422): 1.57e-106: 324: 18.65
+	Hs
		1039064 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		KCC2D_HUMAN (23-343): 2.22e-92: 289: 25.93
+	Mm
		682109 GRDN_MOUSE (97-978): 2.88e-27: 123: 13.55		AKT1_MOUSE (2-425): 1.96e-108: 330: 16.71
+	Hs
		681881 GRDN_HUMAN (292-1148): 1.79e-27: 123: 10.58		AKT1_HUMAN (2-425): 8.17e-108: 328: 16.71
+	Hs
		325758 GRDN_HUMAN (292-1148): 1.79e-27: 123: 10.58		LATS1_HUMAN (1-372): 1.13e-100: 326: 21.96
+	Hs
		325612 MYH8_HUMAN (506-1225): 1.25e-26: 121: 9.79		LATS1_HUMAN (1-372): 1.13e-100: 326: 21.96
+	Hs
		568689 GRDN_HUMAN (292-1148): 1.79e-27: 123: 10.58		KAPCA_HUMAN (3-388): 6.94e-101: 306: 19.39
+	Hs
		325611 MYH6_HUMAN (732-1205): 1.98e-18: 94.1: 12.89		LATS1_HUMAN (1-372): 1.13e-100: 326: 21.96
+	Hs
		325609 MYH7_HUMAN (784-1202): 5.49e-18: 92.5: 9.31		LATS1_HUMAN (1-372): 1.13e-100: 326: 21.96
+	Hs
		528408 MYH8_HUMAN (506-1225): 1.25e-26: 121: 9.79		STK4_HUMAN (3-372): 2.29e-94: 294: 24.46
+	Hs
		528409 MYH8_HUMAN (506-1225): 1.25e-26: 121: 9.79		STK3_HUMAN (21-363): 2.37e-92: 289: 24.93
+	Hs
		725223 MYH10_HUMAN (45-667): 4.85e-21: 102: 10.17		MARK4_HUMAN (16-392): 1.16e-96: 307: 23.81
+	Hs
		568568 MYH10_HUMAN (45-667): 4.85e-21: 102: 10.17		KAPCA_HUMAN (3-388): 6.94e-101: 306: 19.39
+	Hs
		528369 MYH6_HUMAN (732-1205): 1.98e-18: 94.1: 12.89		STK4_HUMAN (3-372): 2.29e-94: 294: 24.46
+	Hs
		528371 MYH6_HUMAN (732-1205): 1.98e-18: 94.1: 12.89		STK3_HUMAN (21-363): 2.37e-92: 289: 24.93
+	Hs
		1057397 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		NEK6_HUMAN (13-332): 2.69e-40: 147: 30.93
+	Hs
		1057328 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		NEK7_HUMAN (7-332): 6.46e-39: 144: 30.12
+	Hs
		1057325 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		NEK9_HUMAN (11-351): 1.03e-35: 142: 29.86
+	Hs
		1057297 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		NEK10_HUMAN (25-362): 2.92e-27: 117: 28.41
+	Hs
		851522 GRDN_HUMAN (292-1148): 1.79e-27: 123: 10.58		NEK4_HUMAN (21-344): 3.04e-35: 140: 30.86