HitPredict

Interactor 1: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50

Interactor 2: HSP79 (P32590)
Heat shock protein homolog SSE2
Gene: SSE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1312 Sc			1 693
+	Sc
		521119 RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00		HSP7F_YEAST (1-693): 0: 1007: 75.61
+	Hs
		504509 RAD50_HUMAN (1-1312): 2e-86: 310: 25.28		HSP7C_HUMAN (2-645): 0: 851: 26.92
+	Hs
		504086 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		HSP7C_HUMAN (2-645): 0: 851: 26.92
+	Sc
		630954 USO1_YEAST (230-1038): 2.47e-09: 64.3: 20.75		HSP7F_YEAST (1-693): 0: 1007: 75.61
+	Hs
		64578 MYH7B_HUMAN (254-1211): 4.86e-30: 132: 10.10		HSP7C_HUMAN (2-645): 0: 851: 26.92
+	Hs
		503376 DESP_HUMAN (179-757): 9.93e-12: 72.3: 11.71		HSP7C_HUMAN (2-645): 0: 851: 26.92
+	Sc
		449877 RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00		HSP73_YEAST (1-642): 1.34e-73: 252: 28.55
+	Sc
		493049 RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00		HSP72_YEAST (1-429): 1.15e-71: 246: 34.95
+	Sc
		490162 RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00		HSP71_YEAST (1-429): 5.26e-71: 244: 34.72
+	Sc
		493298 USO1_YEAST (230-1038): 2.47e-09: 64.3: 20.75		HSP72_YEAST (1-429): 1.15e-71: 246: 34.95
+	Sc
		490455 USO1_YEAST (230-1038): 2.47e-09: 64.3: 20.75		HSP71_YEAST (1-429): 5.26e-71: 244: 34.72