Interactor 1: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50
Interactor 2: MRE11 (P32829)
Double-strand break repair protein MRE11 (EC 3.1.-.-)
Gene: MRE11
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.995 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11470800, 22705791, 26901759, 21892167, 7625279, 11741545, 7789757, 9931460, 11805837, 25231868, 11454871, 14992724, 9755192, 33980827, 25527408, 11430828, 9845372, 10219078, 15126391, 16143598 and 15 others
more... |
| Identification Methods | molecular sieving, biochemical, anti tag coimmunoprecipitation, pull down, two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_23~Metallophos, AAA_23~Mre11_DNA_bind, Metallophos~SbcC_Walker_B |
| Common GO terms | GO:0000723 - telomere maintenance GO:0003691 - double-stranded telomeric DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion and 11 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
