HitPredict

Interactor 1: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50

Interactor 2: CDC14 (Q00684)
Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)
Gene: CDC14

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21127052
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1312 Sc			1 551
+	Hs
		1057427 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		CC14A_HUMAN (12-541): 5.18e-161: 473: 27.13
+	Hs
		1272018 RAD50_HUMAN (1-1312): 2e-86: 310: 25.28		DUS23_HUMAN (173-334): 4.6e-36: 133: 20.99
+	Mm
		139399 GRDN_MOUSE (97-978): 2.88e-27: 123: 13.55		PTEN_MOUSE (152-540): 4.63e-74: 242: 14.53
+	Hs
		1113841 GRDN_HUMAN (292-1148): 1.79e-27: 123: 10.58		DUS16_HUMAN (192-546): 2.49e-65: 226: 15.39
+	Hs
		1057333 SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78		PTPM1_HUMAN (189-326): 2.73e-31: 121: 23.65
+	Hs
		725123 MYH10_HUMAN (45-667): 4.85e-21: 102: 10.17		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Hs
		551649 DESP_HUMAN (179-757): 9.93e-12: 72.3: 11.71		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Hs
		725210 MYH10_HUMAN (45-667): 4.85e-21: 102: 10.17		SSH1_HUMAN (212-450): 7.58e-41: 160: 10.93
+	Hs
		724891 MYH9_HUMAN (50-565): 3.03e-17: 90.2: 7.20		SSH2_HUMAN (152-530): 4.75e-38: 151: 14.00
+	Hs
		260524 MYH9_HUMAN (50-565): 3.03e-17: 90.2: 7.20		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		253766 MYH13_HUMAN (51-510): 1.18e-09: 65.2: 9.74		AUXI_HUMAN (145-389): 9.52e-40: 156: 14.73
+	Hs
		551686 DESP_HUMAN (179-757): 9.93e-12: 72.3: 11.71		DUS4_HUMAN (189-397): 9.77e-38: 145: 16.51