Interactor 1: EI2BD (P12754)
Translation initiation factor eIF2B subunit delta (GCD complex subunit GCD2) (Guanine nucleotide exchange factor subunit GCD2) (eIF2B GDP-GTP exchange factor subunit delta)
Gene: GCD2

Interactor 2: EI2BE (P32501)
Translation initiation factor eIF2B subunit epsilon (GCD complex subunit GCD6) (Guanine nucleotide exchange factor subunit GCD6) (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene: GCD6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 8336705, 11805826, 11805837, 16429126, 24852487, 20805354, 23263984, 10805739, 10852917, 16554755, 37968396, 14759368
Identification Methods coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~NTP_transferase
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
GO:0006446 - regulation of translational initiation
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 651
Sc

1 712
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024