Interactor 1: EI2BD (P12754)
Translation initiation factor eIF2B subunit delta (GCD complex subunit GCD2) (Guanine nucleotide exchange factor subunit GCD2) (eIF2B GDP-GTP exchange factor subunit delta)
Gene: GCD2

Interactor 2: EI2BB (P32502)
Translation initiation factor eIF2B subunit beta (GCD complex subunit GCD7) (Guanine nucleotide exchange factor subunit GCD7) (eIF2B GDP-GTP exchange factor subunit beta)
Gene: GCD7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 11283351, 11805837, 8336705, 16429126, 18467557, 37968396, 20805354, 23263984, 16554755, 24852487, 18563728
Identification Methods two hybrid pooling approach, anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, two hybrid, pull down, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
GO:0006446 - regulation of translational initiation
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 651
Sc

1 381
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc
+ Dm
+ Sc
+ Hv
+ Ce

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Last updated: 15 Jul 2024