Interactor 1: SKI (P12755)
Ski oncogene (Proto-oncogene c-Ski)
Gene: SKI
Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12874272, 10485843, 33961781, 12732634, 10575014, 14699069, 17283070, 18729074, 25670202, 28468752, 19032343, 21149449, 20959473, 12764135, 26977879 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MH2~c-SKI_SMAD_bind |
| Common GO terms | GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex and 8 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
