Interactor 1: SKI (P12755)
Ski oncogene (Proto-oncogene c-Ski)
Gene: SKI

Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 12874272, 14699069, 12426322
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH2~c-SKI_SMAD_bind
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 7 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 728
Hs

1 465
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024