HitPredict

Interactor 1: SKI (P12755)
Ski oncogene (Proto-oncogene c-Ski)
Gene: SKI

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	11430826, 21149449, 14525983, 10049357
Identification Methods	pull down, affinity chromatography technology, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0017053 - transcription repressor complex GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 1273
+	Hs
		521388 SKIL_HUMAN (14-714): 0: 810: 37.27		SIN3A_HUMAN (1-1273): 0: 1545: 100.00