HitPredict

Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 892 Hs			1 326
+	Hs
		521464 ACTN1_HUMAN (1-892): 0: 697: 100.00		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		211495 ACTN4_HUMAN (11-892): 0: 642: 86.74		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		282506 ACTN1_HUMAN (1-892): 0: 697: 100.00		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		164573 SPTN2_HUMAN (225-763): 1.02e-15: 84.3: 14.42		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717709 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718187 SPTN4_HUMAN (173-588): 8.58e-09: 62: 10.82		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		282627 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		963368 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13