Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1
Interactor 2: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.740 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25910212 |
| Identification Methods | two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~CH, CH~EF-hand_7, CH~EFhand_Ca_insen, CH~Spectrin, EF-hand_6~EF-hand_7, EF-hand_7~EFhand_Ca_insen, EFhand_Ca_insen~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin |
| Common GO terms | GO:0005178 - integrin binding GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005829 - cytosol GO:0005925 - focal adhesion and 15 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
 |
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
