Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 17311919
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0098978 - glutamatergic synapse
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 892
Hs

1 1212
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024