HitPredict

Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	34189442, 17082780
Identification Methods	unspecified method, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042803 - protein homodimerization activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 892 Hs			1 358
+	Hs
		211531 ACTN4_HUMAN (11-892): 0: 642: 86.74		CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00
+	Hs
		521460 ACTN1_HUMAN (1-892): 0: 697: 100.00		ATF2_HUMAN (46-352): 2.46e-30: 122: 10.97
+	Hs
		211491 ACTN4_HUMAN (11-892): 0: 642: 86.74		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61
+	Hs
		831226 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00
+	Mm
		862830 SPTB2_MOUSE (196-761): 1.13e-14: 81.2: 12.88		CEBPA_MOUSE (1-358): 4.3e-64: 209: 91.19
+	Hs
		164565 SPTN2_HUMAN (225-763): 1.02e-15: 84.3: 14.42		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61