Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16944923
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Spectrin~ZU5
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0030054 - cell junction
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 892
Hs

1 1748
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Ce
+ Ce
+ Ce
+ Mm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024