HitPredict

Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005911 - cell-cell junction GO:0042803 - protein homodimerization activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 892 Hs			1 914
+	Hs
		211665 ACTN4_HUMAN (11-892): 0: 642: 86.74		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		993295 ACTN3_HUMAN (18-892): 0: 642: 78.51		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725699 ACTN2_HUMAN (10-892): 0: 640: 80.29		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		164666 SPTN2_HUMAN (225-763): 1.02e-15: 84.3: 14.42		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963418 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		506843 SPTB1_HUMAN (235-847): 3.12e-09: 63.1: 10.29		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1329039 SPTN4_HUMAN (173-588): 8.58e-09: 62: 10.82		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963335 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14