Interactor 1: ACE (P12821)
Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]
Gene: ACE

Interactor 2: BKRB2 (P30411)
B2 bradykinin receptor (B2R) (BK-2 receptor)
Gene: BDKRB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 17077303
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0019229 - regulation of vasoconstriction
GO:0042310 - vasoconstriction
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1306
Hs

1 391
+ Hs
+ Hs

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Last updated: 15 Jul 2024