HitPredict

Interactor 1: H14 (P10412)
Histone H1.4 (Histone H1b) (Histone H1s-4)
Gene: H1-4

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.-) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 40437099
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0042826 - histone deacetylase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 1912
+	Hs
		596106 H12_HUMAN (1-177): 2.51e-23: 94.7: 88.76		CHD4_HUMAN (1-1912): 0: 1708: 100.00
+	Hs
		1037154 H11_HUMAN (38-148): 9.74e-18: 80.1: 75.68		CHD4_HUMAN (1-1912): 0: 1708: 100.00
+	Hs
		521664 H14_HUMAN (1-115): 2.96e-23: 94.7: 100.00		CHD3_HUMAN (20-1905): 0: 1570: 66.98
+	Hs
		596068 H12_HUMAN (1-177): 2.51e-23: 94.7: 88.76		CHD3_HUMAN (20-1905): 0: 1570: 66.98
+	Hs
		243520 H14_HUMAN (1-115): 2.96e-23: 94.7: 100.00		SMCA5_HUMAN (584-1624): 0: 776: 26.27