HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 25468996, 10744074, 31286874, 21685945, 18057010
Identification Methods proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0009410 - response to xenobiotic stimulus
GO:0030054 - cell junction
GO:0034332 - adherens junction organization
GO:0045296 - cadherin binding
and 4 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 882
Hs

1 536
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024