HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: CTNA2 (P26232)
Catenin alpha-2 (Alpha N-catenin) (Alpha-catenin-related protein)
Gene: CTNNA2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25468996, 34591612
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction GO:0008013 - beta-catenin binding GO:0015629 - actin cytoskeleton GO:0016342 - catenin complex GO:0045296 - cadherin binding and 1 others more... GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Hs			1 953
+	Hs
		521757 CADH1_HUMAN (1-882): 0: 836: 100.00		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Hs
		522254 CADH1_HUMAN (1-882): 0: 836: 100.00		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Mm
		454942 CADH1_MOUSE (1-882): 0: 799: 81.45		CTNA1_MOUSE (8-952): 0: 946: 78.12
+	Hs
		580206 CADH2_HUMAN (28-881): 0: 769: 45.86		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Hs
		580266 CADH2_HUMAN (28-881): 0: 769: 45.86		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Hs
		606300 CADH3_HUMAN (3-882): 0: 716: 53.06		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Hs
		606311 CADH3_HUMAN (3-882): 0: 716: 53.06		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Hs
		521714 CADH1_HUMAN (1-882): 0: 836: 100.00		VINC_HUMAN (15-911): 0: 586: 19.92
+	Hs
		640751 PCDA8_HUMAN (379-862): 3.62e-64: 235: 16.63		CTNA2_HUMAN (1-953): 0: 1082: 100.00
+	Hs
		640703 CADH5_HUMAN (30-511): 8.2e-52: 196: 20.91		CTNA2_HUMAN (1-953): 0: 1082: 100.00
+	Hs
		640714 CAD12_HUMAN (1-365): 6.76e-47: 182: 19.79		CTNA2_HUMAN (1-953): 0: 1082: 100.00
+	Hs
		640713 CADH8_HUMAN (1-365): 8.09e-45: 175: 20.84		CTNA2_HUMAN (1-953): 0: 1082: 100.00
+	Hs
		702744 CADH5_HUMAN (30-511): 8.2e-52: 196: 20.91		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Mm
		640688 CADH5_MOUSE (30-511): 2.45e-49: 189: 21.06		CTNA1_MOUSE (8-952): 0: 946: 78.12
+	Hs
		716641 CAD12_HUMAN (1-365): 6.76e-47: 182: 19.79		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Hs
		716640 CADH8_HUMAN (1-365): 8.09e-45: 175: 20.84		CTNA1_HUMAN (8-952): 0: 949: 78.12
+	Hs
		1355726 CAD10_HUMAN (1-365): 2.8e-52: 198: 17.69		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Hs
		877559 CAD12_HUMAN (1-365): 6.76e-47: 182: 19.79		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Hs
		877527 CADH4_HUMAN (4-371): 7.07e-38: 155: 15.61		CTNA3_HUMAN (3-949): 0: 910: 57.55
+	Hs
		575694 CADH5_HUMAN (30-511): 8.2e-52: 196: 20.91		VINC_HUMAN (15-911): 0: 586: 19.92