HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25468996, 21376238
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000902 - cell morphogenesis GO:0016020 - membrane GO:0030054 - cell junction GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 504
+	Hs
		606302 CADH3_HUMAN (3-882): 0: 716: 53.06		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		606310 CADH3_HUMAN (3-882): 0: 716: 53.06		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		521992 CADH1_HUMAN (1-882): 0: 836: 100.00		MAGI3_HUMAN (69-270): 5.85e-40: 156: 21.64
+	Hs
		522143 CADH1_HUMAN (1-882): 0: 836: 100.00		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		522229 CADH1_HUMAN (1-882): 0: 836: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61