Interactor 1: PEP5 (P12868)
E3 ubiquitin-protein ligase PEP5 (EC 2.3.2.27) (Carboxypeptidase Y-deficient protein 5) (Histone E3 ligase PEP5) (RING-type E3 ubiquitin transferase PEP5) (Vacuolar biogenesis protein END1) (Vacuolar morphogenesis protein 1) (Vacuolar protein sorting-associated protein 11) (Vacuolar protein-targeting protein 11)
Gene: PEP5
Interactor 2: VPS41 (P38959)
Vacuolar protein sorting-associated protein 41 (Vacuolar morphogenesis protein 2)
Gene: VPS41
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11805826, 10944212, 21325627, 25324549, 16429126, 27428774, 23417307, 17488625, 30269949, 33513092, 19193765, 37968396, 36098503, 20604902, 21079247 |
| Identification Methods | tandem affinity purification, affinity chromatography technology, pull down, two hybrid, biochemical, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000329 - fungal-type vacuole membrane GO:0005768 - endosome GO:0007033 - vacuole organization GO:0030897 - HOPS complex GO:0035542 - regulation of SNARE complex assembly and 2 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
