HitPredict

Interactor 1: A1Z7C4 (A1Z7C4)
LDL receptor protein 1, isoform G
Gene: LRP1

Interactor 2: LAMB1 (P11046)
Laminin subunit beta-1 (Laminin B1 chain)
Gene: LanB1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Laminin_EGF~Ldl_recept_b
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4730 Dm			1 1788
+	Dm
		52252 A1Z7C4_DROME (1-4730): 0: 3189: 100.00		LAMC1_DROME (900-1784): 1.4e-55: 216: 17.33
+	Dm
		52257 A1Z7C4_DROME (1-4730): 0: 3189: 100.00		LAMA_DROME (1048-1301): 6.76e-09: 63.4: 15.07
+	Dm
		53032 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		LAMB1_DROME (1-1788): 0: 972: 100.00
+	Hs
		877404 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		LAMB2_HUMAN (36-1787): 0: 841: 38.62
+	Hs
		502808 NID1_HUMAN (2667-2905): 5.06e-09: 65.2: 12.25		LAMC1_HUMAN (856-1788): 2.52e-78: 289: 22.00
+	Mm
		358675 NID1_MOUSE (2670-2905): 9.15e-10: 67.6: 10.79		LAMC1_MOUSE (856-1788): 5.41e-76: 282: 21.92
+	Hs
		804372 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC3_HUMAN (251-1110): 2.33e-57: 222: 12.48
+	Hs
		980576 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		NOTC3_HUMAN (251-1110): 2.33e-57: 222: 12.48
+	Hs
		992726 LRP1_HUMAN (48-342): 8.07e-09: 64.9: 11.15		NOTC3_HUMAN (251-1110): 2.33e-57: 222: 12.48
+	Dm
		53031 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		NOTCH_DROME (525-1301): 3.26e-51: 202: 12.25
+	Dm
		422964 Q9W4Y4_DROME (60-183): 3.46e-09: 65.9: 37.10		NOTCH_DROME (525-1301): 3.26e-51: 202: 12.25
+	Hs
		537530 NID1_HUMAN (2667-2905): 5.06e-09: 65.2: 12.25		LAMC3_HUMAN (959-1785): 4.54e-31: 136: 14.39
+	Hs
		804213 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC2_HUMAN (303-756): 1.9e-28: 127: 10.89
+	Hs
		804163 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC1_HUMAN (303-662): 6.68e-21: 103: 11.91
+	Mm
		489637 NID1_MOUSE (2670-2905): 9.15e-10: 67.6: 10.79		PGBM_MOUSE (288-417): 2.65e-16: 88: 27.21
+	Hs
		317789 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		NET1_HUMAN (676-826): 4.19e-09: 63.4: 14.38
+	Dm
		53035 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		LAMA_DROME (1048-1301): 6.76e-09: 63.4: 15.07