HitPredict

Interactor 1: A1Z7C4 (A1Z7C4)
LDL receptor protein 1, isoform G
Gene: LRP1

Interactor 2: LAMC1 (P15215)
Laminin subunit gamma-1 (Laminin B2 chain)
Gene: LanB2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Laminin_EGF~Ldl_recept_b
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4730 Dm			1 1639
+	Dm
		52251 A1Z7C4_DROME (1-4730): 0: 3189: 100.00		LAMB1_DROME (16-1633): 1.26e-171: 566: 18.92
+	Dm
		52257 A1Z7C4_DROME (1-4730): 0: 3189: 100.00		LAMA_DROME (260-419): 1.16e-09: 65.7: 20.86
+	Hs
		502808 NID1_HUMAN (2667-2905): 5.06e-09: 65.2: 12.25		LAMC1_HUMAN (54-1638): 0: 870: 39.56
+	Mm
		358675 NID1_MOUSE (2670-2905): 9.15e-10: 67.6: 10.79		LAMC1_MOUSE (52-1638): 0: 861: 40.26
+	Dm
		53032 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		LAMB1_DROME (16-1633): 1.26e-171: 566: 18.92
+	Hs
		877404 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		LAMB2_HUMAN (271-1596): 8.37e-97: 348: 17.42
+	Hs
		537530 NID1_HUMAN (2667-2905): 5.06e-09: 65.2: 12.25		LAMC3_HUMAN (358-1637): 2.33e-69: 260: 16.10
+	Hs
		804163 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Hs
		804372 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		980576 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		992726 LRP1_HUMAN (48-342): 8.07e-09: 64.9: 11.15		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		804213 NOTC1_HUMAN (109-323): 1.91e-11: 73.4: 13.10		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Dm
		53031 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		NOTCH_DROME (862-1159): 1.92e-16: 88: 14.68
+	Dm
		422964 Q9W4Y4_DROME (60-183): 3.46e-09: 65.9: 37.10		NOTCH_DROME (862-1159): 1.92e-16: 88: 14.68
+	Hs
		317789 NOTC2_HUMAN (3-371): 3.23e-11: 72.6: 9.70		NET1_HUMAN (608-794): 3.8e-09: 63.4: 14.14
+	Dm
		53035 NDG_DROME (3365-3600): 6.8e-10: 67.9: 13.64		LAMA_DROME (260-419): 1.16e-09: 65.7: 20.86
+	Mm
		489637 NID1_MOUSE (2670-2905): 9.15e-10: 67.6: 10.79		PGBM_MOUSE (405-650): 7.29e-09: 63.4: 17.67