HitPredict

Interactor 1: MYH7 (P12883)
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Gene: MYH7

Interactor 2: MYH7 (P12883)
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Gene: MYH7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 23980194
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Myosin_head~Myosin_head, Myosin_N~Myosin_head, Myosin_head~Myosin_tail_1, Myosin_N~Myosin_tail_1, Myosin_tail_1~Myosin_tail_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0001725 - stress fiber
GO:0002026 - regulation of the force of heart contraction
GO:0002027 - regulation of heart rate
GO:0003009 - skeletal muscle contraction
and 23 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1935
Hs

1 1935
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024