Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC
Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.60 | 1.00 | 0.778 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~Y_phosphatase, SH2~SH2, SH2~Y_phosphatase, SH2~SH3_1 |
Common GO terms | GO:0005158 - insulin receptor binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007173 - epidermal growth factor receptor signaling pathway and 9 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
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Last updated: 15 Jul 2024