HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	10847592, 11158331
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0030331 - nuclear estrogen receptor binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 2063
+	Hs
		522749 SRC_HUMAN (1-536): 0: 651: 100.00		MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47
+	Hs
		411582 LCK_HUMAN (75-534): 0: 552: 58.48		MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47
+	Hs
		433560 LYN_HUMAN (1-531): 0: 532: 52.44		MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47
+	Hs
		203198 LCK_HUMAN (75-534): 0: 552: 58.48		SYNJ1_HUMAN (1399-1898): 1.37e-10: 69: 15.40
+	Hs
		337335 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47
+	Hs
		297808 LYN_HUMAN (1-531): 0: 532: 52.44		K0754_HUMAN (159-398): 1.31e-13: 79.3: 12.92
+	Hs
		434084 LYN_HUMAN (1-531): 0: 532: 52.44		SRRM2_HUMAN (1328-2061): 5.87e-09: 63.7: 10.47
+	Hs
		782839 CSK_HUMAN (84-525): 2.44e-172: 496: 39.16		NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11
+	Hs
		996575 ITK_HUMAN (54-525): 1.53e-160: 472: 34.23		SRRM2_HUMAN (1328-2061): 5.87e-09: 63.7: 10.47