HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19419966
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0007165 - signal transduction GO:0045087 - innate immune response
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 540
+	Hs
		523197 SRC_HUMAN (1-536): 0: 651: 100.00		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		337495 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		522749 SRC_HUMAN (1-536): 0: 651: 100.00		MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90
+	Hs
		523118 SRC_HUMAN (1-536): 0: 651: 100.00		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		412404 FYN_HUMAN (1-536): 0: 598: 68.39		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		297808 LYN_HUMAN (1-531): 0: 532: 52.44		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		442894 HCK_HUMAN (1-531): 0: 569: 55.22		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		412362 FYN_HUMAN (1-536): 0: 598: 68.39		MAGE1_HUMAN (183-537): 6.13e-11: 67.2: 9.58
+	Hs
		411582 LCK_HUMAN (75-534): 0: 552: 58.48		MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90
+	Hs
		433853 LYN_HUMAN (1-531): 0: 532: 52.44		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Hs
		203198 LCK_HUMAN (75-534): 0: 552: 58.48		SYNJ1_HUMAN (196-539): 7.02e-12: 70.6: 13.41
+	Hs
		337496 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		433560 LYN_HUMAN (1-531): 0: 532: 52.44		MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90
+	Hs
		337590 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Mm
		101424 LYN_MOUSE (1-531): 0: 535: 52.26		F8VPR5_MOUSE (82-395): 1.45e-11: 69.8: 14.24
+	Hs
		337335 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		MUC1_HUMAN (160-534): 7.43e-16: 83.3: 10.90
+	Hs
		789012 TEC_HUMAN (83-528): 6.43e-155: 458: 37.36		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		782820 CSK_HUMAN (84-525): 2.44e-172: 496: 39.16		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58