Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: PTPR2 (Q92932)
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (Islet cell autoantigen-related protein) (IAR) (ICAAR) (Phogrin) [Cleaved into: IA-2beta60]
Gene: PTPRN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Y_phosphatase, SH2~Y_phosphatase
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 536
Hs

1 1015
+ Hs
+ Rn
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Rn
+ Hs
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024