HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 29545793, 10635328, 22447928, 11418661
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
and 5 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 536
Hs

1 522
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024