HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: BBX (Q8WY36)
HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2)
Gene: BBX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30585729
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 941
+	Hs
		523586 XRCC6_HUMAN (1-609): 0: 666: 100.00		SOX2_HUMAN (39-325): 5.4e-55: 195: 17.47
+	Mm
		617176 XRCC6_MOUSE (1-609): 0: 647: 82.92		SOX2_MOUSE (39-325): 1.67e-55: 197: 17.12
+	Hs
		523951 XRCC6_HUMAN (1-609): 0: 666: 100.00		CIC_HUMAN (48-324): 1.44e-38: 158: 24.83
+	Hs
		524832 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		SOX2_HUMAN (39-325): 5.4e-55: 195: 17.47
+	Hs
		525025 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		CIC_HUMAN (48-324): 1.44e-38: 158: 24.83